The generalized logit analysis also revealed that higher BMI strata was significantly associated with female sex (P
The fresh try size for those analyses wasn’t lay good priori, and just the newest offered data out of per analysis were used.
Patient features and adaptation as we age
Desk 1 describes brand new baseline features of one’s 6442 clients reviewed (More file step 1: Dining table S1 will bring such data for each analysis). Full, slightly less than one to-1 / 2 of the latest customers was females, although this ratio improved that have broadening many years. The fresh new mean (SD) period of customers is actually 63.2 (ten.9) age, as well as their anthropometric methods showed that 46.5% were from inside the set of being obese [overall suggest (SD) BMI: 30.step three (5.2) kg/m 2 ], mainly of your central types of (indicate waist circumference, all: 101.8 cm; women: 99.5 cm, men: 103.seven cm). The brand new imply (SD) time of T2D try 7.cuatro (6.7) age, and more than ninety% regarding clients have been acquiring dental antidiabetes medication; the remainder is finding life changes advice only. Imply FBG and you will, like, indicate HbA1c had been over classical non-custom required needs (imply FBG: 9.0 mmol/L; mean HbA1c: eight.4%). Other than HDL-C, SBP, and DBP, mean philosophy of one’s leftover ancient aerobic chance issues (LDL-C and you will triglycerides) have been over the demanded thresholds. These types of thresholds is actually summarized in Profile step 1.
Vintage cardio risk situations and other diligent properties stratified because of the ages, Body mass index, and you will HbA1c range. Philosophy was mode and 95% confidence durations, determined from inside the conveyed strata of situated details (ages, Body mass index, and you will HbA1c). The newest straight dotted outlines in certain maps show target viewpoints necessary of the American Diabetic issues Relationship . Famous people = age; Triangles = BMI; Groups = HbA1c. Abbreviations: Body mass index, bmi; DBP, diastolic blood circulation pressure; FBG, fast blood sugar; HbA1c, glycosylated hemoglobin; HDL, high-occurrence lipoprotein; LDL, low-thickness lipoprotein; SBP, systolic blood pressure level; T2D, type 2 diabetes.
A greater proportion of men than women was in the overweight range (BMI 25 to
Bmi and you will cardio chance points
Triglyceride, SBP, and DBP levels were directly correlated with BMI strata (Figure 1 triangles: charts 8–10, respectively). Conversely, as BMI increased, HDL-C levels decreased (Figure 1 triangles: chart 6); LDL-C levels did not show strong trends with BMI in either direction (Figure 1 triangles: chart 7). The generalized logit analysis confirmed positive associations between increasing BMI strata and SBP, DBP, and triglyceride levels as significant (P
There was an inverse relationship between BMI strata and both age and duration of T2D (Figure 1 triangles: charts 1 and 4, respectively). The generalized logit analysis confirmed these associations were significant (P
HbA1c and you may cardio exposure things
Increased values for the cardiovascular risk factors LDL-C, triglycerides, SBP, and DBP, and decreased levels of HDL-C were related to higher HbA1c strata (Figure 1 circles: charts 7–10 and 6, respectively). In the generalized logit analysis, lower HDL-C (P
The generalized logit analysis also revealed that higher BMI strata was significantly associated with female ...
